72- Vinay Khatri, Fatma Meddeb Mouelhi, Kokou Adjallé , Simon Barnabé and Marc Beauregard Determination of optimal biomass pretreatment strategies for biofuel production: investigation of relationships between surface-exposed polysaccharides and their enzymatic conversion using carbohydrate-binding modules Biotechnol Biofuels (2018) 11:144
Vinay Khatri, Yannick Hébert-Ouellet,
khatri biomasse biotech biofuels 2018.pd
Document Adobe Acrobat 7.4 MB
71- Vinay Khatri, Fatma Meddeb-Mouelhi and Marc Beauregard New-insights into lignocellulosic polymers hydrolysis using fluorescent tagged carbohydrate-binding modules. Sustainable Energy and Fuels (2018) 2: 479
New insights mannans 2018 khatri.pdf
Document Adobe Acrobat 1.2 MB
69- Yannick Hébert-Ouellet, Fatma Meddeb-Mouelhi, Vinay Khatri, Li Cui, Bernard Janse, Kevin MacDonald and Marc Beauregard (2017) Tracking and predicting wood fibers processing by fluorescent carbohydrate binding modules. Green Chemistry (2017) 19:2603
green chemistry yho.pdf
Document Adobe Acrobat 1.7 MB
64- Vinay Khatri, Yannick Hébert-Ouellet, Fatma Meddeb-Mouelhi and Marc Beauregard (2016) Specific tracking of xylan using fluorescent-tagged carbohydrate binding module 15 as molecular probe. Biotechnology for Biofuels 9: 74 2016.
pdf xylanase biotech for biofuels 2016.p
Document Adobe Acrobat 1.6 MB
62- Development of a high-throughput liquid state assay for lipase activity
using natural substrates and rhodamine B (2016) Analytical Biochemistry 496, 25–29
Ximena Zottig, Fatma Meddeb-Mouelhi, Marc Beauregard
ximena rho.pdf
Document Adobe Acrobat 462.9 KB
59- Li Cui, Fatma Meddeb-Mouelhi, Francois Laframboise, and M. Beauregard (2015) Effect of commercial cellulases and refining on kraft pulp properties: Correlations between treatment impacts and enzymatic activity components. Carbohydrate Polymers 115, 193–199.
Li Cui-1er paper 2014.pdf
Document Adobe Acrobat 1.1 MB
58- Meddeb-Mouelhi, F., Moisan, J.K. and Beauregard, M. (2014) A Comparison of Plate Assay Methods for Detecting Extracellular Cellulase and Xylanase Activity. Enzyme and Microbial Technology 66, 16–19.
A comparison of plate assay methods for
Document Adobe Acrobat 728.3 KB
56- David M Charbonneau and Marc Beauregard (2013) "Role of key salt bridges in thermostability of G. thermodenitrificans EstGtA2: Distinctive patterns within the new bacterial lipolytic enzyme family XV". PLOS ONE DOI: 10.1371/journal.pone.0076675
salt bridges david marc PONE-D-13-21380
Document Adobe Acrobat 5.2 MB
55- Korman, Tyler; Sahachartsiri, Bobby; Charbonneau, David M.; Huang, Grace; Beauregard, Marc and Bowie, James. (2013) Dieselzymes: Development of a stable and methanol tolerant lipase for biodiesel production by directed evolution. Biotechnology for Biofuels 6:70 doi:10.1186/1754-6834-6-70
dieselzyme 2013 1754-6834-6-70.pdf
Document Adobe Acrobat 2.1 MB
46- Etienne Dubé, François Shareck, Yves Hurtubise, Claude Daneault and Marc Beauregard* (2008) Homologous cloning, expression and characterization of a laccase and enzymatic decolourization of an indigo dye. Appled Microbiology Biotechnology 79: 597.
Dubé Homologous cloning expression and c
Document Adobe Acrobat 152.8 KB




70- Pierre-Louis Bombecka, Vinay Khatrib†, Fatma Meddeb-Mouelhib†, Daniel Montplaisirc, Aurore Richela and Marc Beauregardb* (2017) Predicting the most appropriate wood biomass for selected industrial applications: comparison of wood, of pulping and of enzymatic treatments using FTCM. Biotech for Biofuels 10: 293.   


68- Laframboise, F., Meddeb-Mouelhi, F., Barnabé, S. and Beauregard, M (2016) Recovery of biomass energy on the farm: Identification of cellulolytic bacteria in agricultural residues for on-site bioethanol production. British Biotechnology Journal, 15(2) 1-8. 

67- Ximena Zottig, Fatma Meddeb-Mouelhi and Marc Beauregard (2017) In silico, biochemical and biophysical characterization of a novel alkalophilic lipase from Aneurinibacillus thermoaerophilus. J. Biotechnol. accepted after minor revision. 

66- Jessica Kelly Moisan, Fatma Meddeb-Mouelhi, Marc Beauregard (2017) Charged Surface Residues Control Denaturation Completeness and Aggregation of Carboxylesterase EstGtA2. Prot. Pept. Letters accepted after minor revision.  

65- Manel Ghribi, Fatma Meddeb-Mouelhi and Marc Beauregard (2016) Paper mill sludge biodiversity: identification and investigation of bacteria producing enzymes for potential applications. Springer Plus 5:1492. 

63- Fatma Meddeb-Mouelhi,Jessica Kelly Moisan, Jodrey Bergeron, Benoit Daoust and Marc Beauregard (2016) Characterization and Structure Elucidation of a Novel Pigment Produced by a Photochromogenic Microbacterium oxydans Strain. Applied Biochemistry and Biotechnology vol XX, 1-15, DOI 10.1007/s12010-016-2167-8 

61- Li Cui, Fatma Meddeb-Mouelhi and Marc Beauregard (2016) Permutation of refining and cellulase treatments determines the overall impact on drainability and strength properties in kraft pulp. Nordic Pulp & Paper Research Journal 31: 315.

60- Meddeb-Mouelhi, F., Moisan, J. K. and Beauregard, M. (2016) Characterization of a Bacterial Community Isolated from Decaying Wood. Brit. Biotechnol. J. 10: 1-14.  Available online at DOI: 10.9734/BBJ/2016/21512.

57- Daniel Agudelo, Philippe Bourassa, Marc Beauregard, Gervais Bérubé and Heidar-Ali Tajmir-Riahi (2013) tRNA Binding to Antitumor Drug Doxorubicin and Its Analogue. PLOS ONE 8(7):e69248. DOI: 10.1371/journal.pone.0069248.

54- Agudelo, Daniel; Beauregard, Marc; Berube, Gervais; Tajmir-Riahi, Heidar-Ali (2013) Antibiotic Doxorubicin and its Derivative Bind Milk β-Lactoglobulin. (2012) J. Photochem. Photobiol. B 117:185-92. doi: 10.1016/j.jphotobiol.2012.09.014 

52- High transformation efficiency of Bacillus subtilis with integrative DNA using glycine betaine as osmoprotectant (2012) F. Meddeb-Mouelhi, C. Dulcey and M. Beauregard. Analytical Biochem. http://dx.doi.org/10.1016/j.ab.2012.01.032

51- N-terminal purification tag alters thermal stability of the carboxylesterase EstGtA2 from G. thermodenitrificans by impairing reversibility of thermal unfolding (2012) David M. Charbonneau, Fatma Meddeb-Mouelhi and Marc Beauregard.  Protein and Peptide Letters 19, 264-269.

 50- Identification of Thermophilic Bacterial Strains Producing Thermotolerant Hydrolytic Enzymes from Manure Compost (2011) David M. Charbonneau, Fatma Meddeb-Mouelhi, Maurice Boissinot, Marc Sirois, and Marc Beauregard.  Ind. J. Microbiology, 52, 41-47.

 49- A Novel Thermostable Carboxylesterase from Geobacillus thermodenitrificans: Evidence for a New Carboxylesterase Family. (2010) David M. Charbonneau, Fatma Meddeb-Mouelhi and Marc Beauregard. J. Biochemistry 148, 299-308. 

48- Charbonneau, D., Beauregard, M. and Tajmir-Riahi, H.A. (2009) Structural analysis of human serum albumin complexes with cationic lipids.  J. Phys. Chem. B, 113, 1777-1784. 

47- Houle, V., Gagnon, M.C., Dubé, E., Hurtubise, Y. and Beauregard, M. (2008) Impact of glycosylation onSaccharomyces cerevisiae endopolygalacturonase PGU1 activity and stability.  Open J. Biotech. 2 (1) 36-42. 

45- Etienne Dubé, François Shareck, Yves Hurtubise, Marc Beauregard and Claude Daneault (2008) Enzyme-based approaches for pitch control in thermomechanical pulping of softwood and pitch removal in process water. J. Chemical Technol. Biotech. 83, 1261-1266.  

44- Etienne Dubé, François Shareck, Yves Hurtubise, Marc Beauregard and Claude Daneault (2008) Decolourization of recalcitrant dyes under alkaline conditions with a bacterial laccase. J. Indust. Microbiol. Biotech. 35, 10, 1123. 

43- J. F. Neault, S. Diamantoglou, M. Beauregard, Sh. Nafisi and H. A. Tajmir-Riahi (2008)

Protein Unfolding in Drug-RNase Complexes.  J. Biomol. Struct. Dyn. 25: 387-394. 

42- C. N. N’ soukpoé-Kossi, C. St-Louis, M. Beauregard, M. Subirade, R. Carpentier, S. Hotchandani, and H. A. Tajmir-Riahi (2006) Resveratrol Binding to Human Serum Albumin.  J. Biomol. Struct. Dyn.  24: 277-283. 

41- Beauregard, M. and Hefford, M.A. (2006) Enhancement of essential amino acid contents in crops by genetic engineering and protein design.  Plant Biotech. J. 4: 561-574. 

40- Habib Khoudi and Marc Beauregard.  (2005) The de novo designed protein MB-1Trp does not accumulate in transgenic alfalfa plants.  Plant Physiol. Biochem. 43: 1039-1043.  

39- Subramanyam, R., Joly, D., Gauthier, A., Beauregard, M. and Carpentier, R.  (2005)  Protective effect of active oxygen scavengers on protein degradation and photochemical function in photosystem I submembrane fractions during light stress.  FEBS Journal 272: 892-902. 


And long time ago, when the boss was young and brilliant: 

19- Beauregard, M., Dupont, C., Teather, R.M. and Hefford, M.A. (1995) Design, expression and initial characterization of MB-1, a de novo protein enriched in essential amino acids. Nature Biotechnology 13, 974-981.